Renal Clearance of Endogenous Creatinine and Doxycycline in Male Volunteers
نویسندگان
چکیده
منابع مشابه
The Renal Clearance of Endogenous "creatinine" in Man.
The existing methods for the analysis of inulin, as well as the requirements for the continuous intravenous infusion of this material, place the inulin clearance method for measuring the glomerular filtration rate beyond the reach of practicality for many laboratories and in general limit clearance observations to relatively short intervals of time. There is a requirement for a simpler clearanc...
متن کاملPlasma chromogen and the endogenous creatinine clearance.
One of the troubles of using the endogenous creatinine clearance to measure the filtration rate is that plasma and serum contain chromogens, other than creatinine, which give a colour with the Jaffe reaction. The creatinine can, however, be isolated by adsorption on Fuller's earth (Gaebler and Keltch, 1928) and subsequently eluted with the alkaline picrate used for colour production (Borsook, 1...
متن کاملThe endogenous creatinine clearance in normal subjects.
In normal subjects the glomerular filtration rate is relatively constant under standard conditions, and there is little or no change when the urine flow 'aries. It follows from this that the excretion rate of substances, which are filtered at the glomerulus and neither reabsorbed from nor secreted into the tubules, is constant. It is these substances which can be used to measure the filtration ...
متن کاملCreatinine clearance in renal disease. A reappraisal.
To determine the validity of endogenous creatinine clearance as a measure of glomerular filtration rate in patients with renal disease 308 simultaneous determinations of inulin clearance and endogenous creatinine clearance were reviewed and analysed. The ratio of creatinine clearance/inulin clearance increased progressively with the decline in inulin clearance, while the finding of a normal end...
متن کاملUtility of endogenous creatinine clearance as a measure of renal function in mice.
BACKGROUND The use of endogenous plasma creatinine levels and creatinine clearance as a tool to evaluate renal function in mice has come under scrutiny as prior studies have reported that the Jaffé alkaline picrate method grossly overestimates true plasma creatinine in mice. As members of the NIDDK Animal Models of Diabetic Complications Consortium (AMDCC), we evaluated the performance and feas...
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ژورنال
عنوان ژورنال: Journal of Medical Sciences
سال: 2003
ISSN: 1682-4474
DOI: 10.3923/jms.2003.283.288